Quark is leading provider of scientific solutions for laboratories across Africa.
Quark is leading provider of scientific solutions for laboratories across Africa.
Great industries are never made from single companies. There is room in space for a lot of winners.
Knowledge is of no value unless you put it into practice.
Shimadzu Journal has been highlighting various collaborative research
projects as well as technical reports and applications from our library since its
launch in October 2013. This issue focuses on food development and contains
information on recent collaborations. In addition, this issue contains
information on other applicable topics, as well as the latest news and
applications.
Pharmaceutical
Acid, base titration by
Automatic Potentiometric Titrator
Sodium hydrogen carbonate is used in antacid or other pharmaceuticals. Here, a sample from commercially sold stomach medicine is titrated with 0.5mol/L sulfuric acid according to Japanese Pharmacopoeia codex 15. The contained sodium hydrogen carbonate is determined by the endpoint, which is the maximum inflexion point on titration curve.
2NaHCO3 + H2SO4 → Na2SO4 + 2H2CO3
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Boric Acid in Pesticide |
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Acid base titration by |
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Boric acid in pesticide is quantified according to JIS K 8863-2007 Boric Acid (Reagent).
After D-Mannitol and water are added to the sample for extraction, it is titrated with sodium hydroxide up to the endpoint. Direct titration for boric acid is difficult because boric acid hardly dissociates acid. Polyols such as mannitol form complexes with boric acid and release hydrogen ions. This operation makes neutralization titration for boric acid possible.The endpoint is the inflexion point on titration curve.
The boric acid in pesticide is calculated from titration volume.
Simultaneous determination of residual solvents in pharmaceutical packaging materials using headspace-GC MS
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In this issue, learn more about:
• The Volumetric Precision Dispenser • HPLC Fittings Kit
• CleanPrep HPLC Columns
• SunShell Guard Cartridge Column
• SunShell Super cially Porous Silica • The Biotech USB-stick
FTIR TALK Vol: 33
TOPICS:
European Pharmacopoeia 9.7 ------- 02
Introduction of Various ATR Measurement Attachments (2) ------- 05
Fourier Transform Infrared Spectrophotometer IRSpirit Advanced Performance UniBloc Balances AP Series ------- 8
In this issue you can read about:
DEGASi High Flow 1000 DEGASi Prep+
TUBI — Tubing Your Way
SMART SAVE® Solvent Recycling Unit
SMART SAVE® Solvent Recycling Unit
MarvelXACT
Osaka University Shimadzu Omics Innovation Research Laboratories
In these laboratories, we aim to actively promote various kinds of collaborative research in order to tackle the issue of extending healthy and active lifespan, focused on the use of omics with metabolomics at its core. Until now, Prof. Fukusaki, who develops applications for metabolomics technology, and Prof. Matsuda, who focusses on data analysis, have been carrying out research together at the Osaka University and Shimadzu Analytical Innovation Research Laboratory. In moving to the new Omics Innovation Research Laboratories, they hope to up the pace of innovation to provide direct solutions to these types of societal prolems.
In the pharmaceutical industry, increasingly rigorous compliance with data integrity (DI) is required by regulatory authorities. In this context, the attention of regulatory authorities with respect to analytical instruments is turning not only to liquid chromato- graphs (LC), gas chromatographs (GC) and other chromatogra- phy equipment, but also to UV-Vis spectrophotometers (UV), Fourier transform infrared spectrophotometers (FTIR) and other spectroscopy equipment.
At Shimadzu, we offer multiple analysis data systems capable of accommodating DI: a database management edition (herein referred to as “LabSolutions DB”) and a client server edition (herein referred to as “LabSolutions CS”). In terms of accommo- dating DI, systems and operations must satisfy the ALCOA princi- ples. Both LabSolutions DB and CS (hereinafter referred to as
LabSolutions DB/CS”) are equipped with functionality to support this. As one example, the Analysis Sequence application was developed to enable measurements in accordance with an analysis sequence created in advance.
With the Analysis Sequence application, the measurement parameters and report format to use in analysis are speci ed in advance, so settings/operational mistakes during measurements can be reduced. Additionally, combination with the report set function also makes it easier to check the logs of operations implemented for consecutive measurements.
This article provides a simple overview of DI, as well as a description of the functionality and role of LabSolutions DB/CS and the Analysis Sequence application.
For Research Use Only. Not for use in dia
For Research Use Only. Not for use in diagnostic procedures.
This publication may contain references to products that are not available in your country. Please contact us to check the availability of these products in your country.
The content of this publication shall not be reproduced, altered or sold for any commercial purpose without the written approval of Shimadzu.
For Research Use Only. Not for use in diagnostic procedures.
This publication may contain references to products that are not available in your country. Please contact us to check the availability of these products in your country.
The content of this publication shall not be reproduced, altered or sold for any commercial purpose without the written approval of Shimadzu.
Company names, products/service names and hlogos used in this publication are trademarks and trade names of Shimadzu Corporation, its subsidiaries or its af liates, whether or not they are used with trademark symbol “TM” or “®”.
Third-party trademarks and trade names may be used in this publication to refer to either the entities or their products/services, whether or not they are used with trademark symbol “TM” or “®”.
Shimadzu disclaims any proprietary interest in trademarks and trade names other than its own.
The information contained herein is provided to you “as is” without warranty of any kind including without limitation warranties as to its accuracy or completeness. Shimadzu does not assume any responsibility or liability for any damage, whether direct or indirect, relating to the use of this publication. This publication is based upon the information available to Shimadzu on or before the date of publication, and subject to change without notice.
Third-party trademarks and trade names may be used in this publication to refer to either the entities or their products/services, whether or not they are used with trademark symbol “TM” or “®”.
Shimadzu disclaims any proprietary interest in trademarks and trade names other than its own.
The information contained herein is provided to you “as is” without warranty of any kind including without limitation warranties as to its accuracy or completeness. Shimadzu does not assume any responsibility or liability for any damage, whether direct or indirect, relating to the use of this publication. This publication is based upon the information available to Shimadzu on or before the date of publication, and subject to change without notice.
gnostic procedures.
This publication may contain references to products that are not available in your country. Please contact us to check the availability of these products in your country.
The content of this publication shall not be reproduced, altered or sold for any commercial purpose without the written approval of Shimadzu.
Company names, products/service names and logos used in this publication are trademarks and trade names of Shimadzu Corporation, its subsidiaries or its af liates, whether or not they are used with trademark symbol “TM” or “®”.
Third-party trademarks and trade names may be used in this publication to refer to either the entities or their products/services, whether or not they are used with trademark symbol “TM” or “®”.
Shimadzu disclaims any proprietary interest in trademarks and trade names other than its own.
The information contained herein is provided to you “as is” without warranty of any kind including without limitation warranties as to its accuracy or completeness. Shimadzu does not assume any responsibility or liability for any damage, whether direct or indirect, relating to the use of this publication. This publication is based upon the information available to Shimadzu on or before the date of publication, and subject to change without notice.
For Research Use Only. Not for use in diagnostic procedures.
This publication may contain references to products that are not available in your country. Please contact us to check the availability of these products in your country.
The content of this publication shall not be reproduced, altered or sold for any commercial purpose without the written approval of Shimadzu.
Company names, products/service names and logos used in this publication are trademarks and trade names of Shimadzu Corporation, its subsidiaries or its af liates, whether or not they are used with trademark symbol “TM” or “®”.
Third-party trademarks and trade names may be used in this publication to refer to either the entities or their products/services, whether or not they are used with trademark symbol “TM” or “®”.
Shimadzu disclaims any proprietary interest in trademarks and trade names other than its own.
The information contained herein is provided to you “as is” without warranty of any kind including without limitation warranties as to its accuracy or completeness. Shimadzu does not assume any responsibility or liability for any damage, whether direct or indirect, relating to the use of this publication. This publication is based upon the information available to Shimadzu on or before the date of publication, and subject to change without notice.
WELCOME TO DIGITAL CLASSROOMS
Digital classrooms shares and discuss various aspects of analytical technologies, applications, solutions, ow of information and compliance. Choose any subject, any classroom based on your interest in speci c Industry or Technology. These are specially designed modules based on demand by members of various industries.
Learn at your pace and convenience.
Anytime. Anywhere.
https://www.an.shimadzu.com/rs/119-VAD-470/images/Shimadzu-Digital-Classrooms-e-Brochure.pdf
DownloadAnalysis of 37 FAMEs using 6 Types of Capillary Columns
Interview with Dr. Pan Yi
We all share the same working concept and goals
Interview with Dr. Giusti and Dr. Piparo
Listen to our needs and problems, and constantly look to progress in the development of new instruments and concepts
The methods package contains ready-to-use analytical conditions and sample pretreatment procedures optimized for Shimadzu mass spectrometers and specific analytical applications. Method sets allow you to perform simultaneous analysis of multiple compounds efficiently and quickly. Method packages also support workflow automation by facilitating analysis without having to study separation conditions, optimize MS parameters for each compound, and perform other complex tasks. Shimadzu has developed various method packages suitable for different analytical targets.
DownloadDevelopment of a Boron Nitride Solid Base Catalyst and Evaluation
of its Structure and Solid Basic Properties Using FTIR Spectroscopy ------ 02
Using FTIR Data across Software Platforms ------- 06
Good Spectra and Peak Distortion ------- 08
Q&A Do All ATR Spectra Require ATR Correction?------ 13
Fourier Transform Infrared Spectrophotometer "IRXross" ------ 14
DownloadLeveraging the advanced capabilities of the Brevis GC and the AOC-30i autosampler, this method not only delivers exceptional reproducibility but also enables sustainability, with Brevis GC reducing power consumption by 30% compared to conventional models—even during normal operation.
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pesticides in olive oil. It’s highlight the advantage of cSPE quechers versus the dispersive ones. With the cSPE it is possible to automate the cleaning of samples using Extrahera or semi automated systems like Pressure+ 48.
DownloadTraditional titration and atomic absorption methods for antacid analysis are time-consuming and require complex sample prep.
This application news shows how Shimadzu's EDX-7200 delivers quick, accurate, and user-friendly aluminum quantitation.
Key Benefits:
✅ Simple sample preparation
✅ Results in just a few minutes
✅ High repeatability and accuracy
Strengthening Pharmaceutical Safety with trusted Analytical solutions
Repeated global incidents involving contaminated medicinal syrups have reinforced an urgent need for stricter, multi-level Quality Control (QC) across the pharmaceutical supply chain. To prevent such occurrences, QC must begin at the raw material stage and continue rigorously through manufacturing, excipient evaluation, and finished product testing.
Shimadzo’s 𝙀𝙂/𝘿𝙀𝙂 𝘼𝙣𝙖𝙡𝙮𝙯𝙚𝙧 is designed to support this commitment to safety. With an end-to-end workflow, ready-to-use methods, and simplified reporting, it enables fast, reliable, and compliant analysis of 𝙀𝙩𝙝𝙮𝙡𝙚𝙣𝙚 𝙂𝙡𝙮𝙘𝙤𝙡 (𝙀𝙂) and 𝘿𝙞𝙚𝙩𝙝𝙮𝙡𝙚𝙣𝙚 𝙂𝙡𝙮𝙘𝙤𝙡 (𝘿𝙀𝙂) in pharmaceutical excipients.
The Impact of Automation on Sample Introduction for Trace Contaminant Analysis Yoshiro Hiramatsu discusses how automated GC–MS/MS workflows simplify PFAS testing, improve safety, and boost productivity in routine labs.
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Analysis of Fluorine by EDXRF: Check for Use of PFAS in Textiles & Kitchen Supplies
PFAS are widely used for water and oil repellency in textiles and kitchenware, but their persistence in the environment and potential health risks have raised major concerns.
This application news demonstrates how Shimadzu’s EDX-8100 allows for fast and simple detection of fluorine in consumer products – helping identify possible PFAS use with minimal sample prep.
Key Benefits:
✅ Detects fluorine quickly and easily in coatings
✅ No complicated sample preparation needed
✅ Simple technique to screen for PFAS use
How can milk fat analysis be faster and more reliable? Brevis GC makes it possible. Featuring advanced technology for precise analysis of triglycerides (TGs) and fatty acid methyl esters (FAMEs), along with a robotic autosampler for streamlined automation, it enables your lab to achieve greater speed and accuracy in dairy quality control.
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🚗 Automatic Durability Testing of Rubber Vibration Isolators with EMT Series
Rubber vibration isolators are critical for reducing vibration and shock, but their long-term reliability is often compromised by fatigue and wear.
This application news demonstrates how Shimadzu’s EMT Series and advanced combination test software deliver continuous, automated measurement and high-frequency testing for superior durability evaluation.
Key Advantages:
✅ JIS K 6385-compliant testing
✅ Automated and continuous measurement of static and dynamic properties before and after durability testing
✅ High-frequency capability for advanced fatigue analysis
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🚗 Reliable VOC and SVOC Analysis in Accordance with VDA 278
Unpleasant odors in vehicles are a challenge no one wants to face. Automotive manufacturers address this by following VDA 278 standards, requiring precise estimation of Total Volatile Organic Compounds (TVOC).
The Shimadzu GCMS-QP2050, combined with the TD-30R thermal desorption system and our TVOC calculation tool, ensures consistent and intuitive analysis of VOCs and SVOCs.
DownloadSafety in every drop—Shimadzu’s advanced analytical solutions with Brevis GC ensure end-to-end detection of Ethylene Glycol (EG) and Diethylene Glycol (DEG) in raw materials and oral liquids, 𝗶𝗻 𝗮𝗰𝗰𝗼𝗿𝗱𝗮𝗻𝗰𝗲 𝘄𝗶𝘁𝗵 𝗨𝗦𝗣 𝗼𝗿 𝗜𝗣 𝗺𝗼𝗻𝗼𝗴𝗿𝗮𝗽𝗵 𝘀𝘁𝗮𝗻𝗱𝗮𝗿𝗱𝘀.
With simplified setup, regulatory compliance, and automated test reports, we support efficient EG and DEG analysis to ensure pharma safety.
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The SHIMADZU CORPORATION i-Series LC-2060C 3D system equipped with the RF-20Axs detector, the Shim-pack GIST C18 column and the LCTech AflaCLEAN immunoaffinity columns was used in the described application. The use of post-column photochemical derivatization allowed for a significant increase in the sensitivity of the assays, enabling the detection of even very low concentrations of the analyzed toxins.
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