Technical specifications

Solid Phase Extraction (SPE)
  • Function: 
    Separates analytes from a liquid sample by selectively retaining them on a solid sorbent while allowing the rest of the sample to pass through. 
     
  • Mechanism: 
    Analyte retention is based on interactions (like adsorption, ion exchange, or partitioning) with the sorbent's surface. 
     
  • Key Features:
    • Versatile sorbents: Available in a wide range of materials for different applications, including silica, polymeric, Florisil, and specialty options like CarboPrep and EPH sorbents. 
       
    • High purity: Manufactured with clean sorbents and materials to minimize interference. 
       
    • Reproducibility: Rigorous quality control ensures consistent performance. 
       
    • Formats: Available in cartridges and 96-well plates. 
       
Supported Liquid Extraction (SLE)
  • Function: 
    An efficient form of liquid-liquid extraction in a miniaturized format that removes proteins, phospholipids, and salts from samples.
  • Mechanism: 
    The sample is loaded onto a highly porous diatomaceous earth support, where it diffuses. An immiscible solvent is then added, and the analytes partition between the aqueous and organic phases, followed by elution.
  • Key Features:
    • Simplicity: Faster and easier than traditional liquid-liquid extraction; simply load, wait, and elute.
    • Effective: Quickly removes interferences like proteins and salts.
    • High-throughput: Easily automated for high-throughput laboratories.
    • Versatility: Suitable for a wide range of sample matrices and analyte types.
    • Formats: Available in cartridges and 96-well plates.