LCMS-8050 Liquid Chromatograph Triple Quadrupole Mass Spectrometer (LCMSMS)
Continuing the evolution of Shimadzu's UF technology. Shimadzu introduces LCMS-8050 Triple Quadrupole Mass Spectrometer offering unparalleled measurement speed and high-sensitivity performance.
High sensitivity quantitation delivered at high speed
High speed scanning (UFscanning)
High sensitivity and Positive / Negative Ionization Switching Technology (UFswitching)
High sensitivity and high speed MRM (UF-MRM)
Patented ultra fast technologies (UFMS)
Method packages and databases (Pesticides, Forensic Tox, Veterinary, Met ID and more)
Technical specifications
UFscanning
High-Sensitivity & High-Speed Scanning at 30,000 u/sec
Simultaneous Quantitative and Qualitative Analysis Simultaneous High-Speed Screening of 12 Toxicological Drugs
The LCMS-8050 is capable of simultaneously obtaining both qualitative and quantitative information in a single analysis. Acquisition occurs so rapidly that MS/MS scans and MRM measurements can be performed concurrently while maintaining quantitative accuracy. MS/MS scans are usable and reliable because even at 30,000 u/sec, Shimadzu uses a 0.1 u scan step.
MRM Triggered Product Ion Scanning of a Mixture of 12 Benzodiazepines (1 ng/mL each)
UFswitching
High-Sensitivity & High-Speed Positive/Negative Ionization Switching in 5 msec
Just One Minute per Analysis A Case Study Using High-Speed Positive/Negative Ionization Switching
When performing simultaneous positive/negative ion measurements of multiple components, the proper acquisition of sharp UHPLC peaks depends on rapid polarity switching. The LCMS-8050 minimizes losses due to polarity switching and ensures the collection of sufficient data points for even the narrow peaks obtained with UHPLC, recording accurate peak shapes and allowing excellent reproducibility.
UF-MRM
High-Sensitivity & High-Speed MRM at 555 ch/sec
Detect Target Compounds at Trace-Level Concentrations Simultaneous Analysis of 29 Pesticides for Water Quality Analysis
The LCMS-8050 is capable of simultaneously acquiring 555 MRM transitions per second while maintaining accuracy and precision. Sufficient data points can be collected for quantitation ions, reference ions, and internal standard ions even in chromatographic regions with unresolved peaks. The high sensitivity of the LCMS-8050 allows for trace-level analysis, such as pesticides in drinking water, without the need for sample pre-concentration. This high sensitivity is maintained even when monitoring numerous MRM channels.
The methods package contains ready-to-use analytical conditions and sample pretreatment procedures optimized for Shimadzu mass spectrometers and specific analytical applications. Method sets allow you to perform simultaneous analysis of multiple compounds efficiently and quickly. Method packages also support workflow automation by facilitating analysis without having to study separation conditions, optimize MS parameters for each compound, and perform other complex tasks. Shimadzu has developed various method packages suitable for different analytical targets.